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Paul Pogba and Marcus Rashford have been benched by Ralf Rangnick, with Cristiano Ronaldo starting up front against Brighton.
Manchester United face Brighton in the Premier League, hoping to break into the top four in the race for a Champions League ticket.
Despite the open conflict between Ralf Rangnick and Cristiano Ronaldo in recent weeks, the 37-year-old starts up front and will be eager to end his goal drought.
Ronaldo has gone six games without a goal — his longest stretch in almost a decade.
Anthony Elanga returns to the starting lineup with Fred and Scot McTominay, as Paul Pogba and Marcus Rashford are benched.
Edinson Cavani is sidelined with an injury, although Rangnick has Jesse Lingard and Juan Mata on the bench.
Neal Maupay spearheads Brighton’s attack, while Leandro Trossard, Yves Bissouma, and Alexis Mac Allister all make their debuts for Graham Potter’s side.
MANCHESTER UNITED XI: De Gea, Dalot, Maguire, Varane, Telles, McTominay, Fred, Fernandes, Elanga, Sancho, and Ronaldo
Henderson, Telles, Jones, Lindelof, Wan-Bissaka, Lingard, Mata, Pogba, and Rashford are available as substitutes.
Sanchez, Cucurella, Dunk, Webster, Veltman, Mac Allister, Moder, Bissouma, Gross, Maupay, Trossard. BRIGHTON XI: Sanchez, Cucurella, Dunk, Webster, Veltman, Mac Allister, Moder, Bissouma, Gross, Maupay, Trossard.
Alzate, Lamptey, Caicedo, Lallana, Duffy, March, Ferguson, Welbeck, Steele are available as substitutes.